<p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;text-align:left"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal">&nbsp; &nbsp;</span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;text-align:left"><span style="color:#000000;font-weight:700;text-decoration:none;vertical-align:baseline;font-size:14pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal">FORMEVET ANTIPARASSITARIO FIPRALONE DUO SPOT ON PER CANI DI TAGLIA MEDIA DA 10 A 20 KG 4 PIPETTE DA 1,34 ML</span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;height:10pt;text-align:left"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal"></span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;text-align:left"><span style="color:#000000;font-weight:700;text-decoration:none;vertical-align:baseline;font-size:11pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal">Descrizione:</span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;text-align:left"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal">Formevet Antiparassitario Fipralone Duo Spot On per cani di taglia media da 10 a 20 kg 4 pipette da 1,34 ml</span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;height:10pt;text-align:left"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal"></span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;text-align:left"><span style="color:#000000;font-weight:700;text-decoration:none;vertical-align:baseline;font-size:11pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal">Dettagli:</span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;text-align:left"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal">Antiparassitario per il trattamento delle infestazioni da pulci e zecche.</span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;text-align:left"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal">Fipralone Duo Spot On agisce sterilizzando le pulci adulte, inibendo lo sviluppo di uova e larve nell&rsquo;ambiente dopo l&rsquo;applicazione sull&rsquo;animale e interrompendo cos&igrave; il loro ciclo di vita e prevenendo il loro perpetuarsi nell&rsquo;ambiente.</span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;text-align:left"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal">Questa azione si protrae per 12 settimane dopo ogni singola applicazione.</span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;text-align:left"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal">Come in tutti gli spot-on di Formevet, anche le pipette di Fipralone Duo Spot On sono trasparenti per un miglior controllo dell&rsquo;erogazione e sono dotate di un sistema salva-goccia che permette un&rsquo;accurata ed uniforme stesura sul dorso dell&rsquo;animale riducendo cos&igrave; il rischio di effetti collaterali come arrossamenti o prurito nel punto di applicazione.</span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;height:10pt;text-align:left"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal"></span></p><p id="h.gjdgxs" style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;text-align:left"><span style="font-size:11pt;font-weight:700">Formato: </span><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal">4 pipette da 1,34 ml</span></p>

<p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;text-align:left"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal">&nbsp; &nbsp;</span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;text-align:left"><span style="color:#000000;font-weight:700;text-decoration:none;vertical-align:baseline;font-size:14pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal">FORMEVET ANTIPARASSITARIO FIPRALONE DUO SPOT ON PER CANI DI TAGLIA GRANDE DA 20 A 40 KG 4 PIPETTE DA 2,68 ML</span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;height:10pt;text-align:left"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal"></span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;text-align:left"><span style="color:#000000;font-weight:700;text-decoration:none;vertical-align:baseline;font-size:11pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal">Descrizione:</span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;text-align:left"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal">Formevet Antiparassitario Fipralone Duo Spot On per cani di taglia grande da 20 a 40 kg 4 pipette da 2,68 ml</span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;height:10pt;text-align:left"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal"></span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;text-align:left"><span style="color:#000000;font-weight:700;text-decoration:none;vertical-align:baseline;font-size:11pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal">Dettagli:</span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;text-align:left"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal">Antiparassitario per il trattamento delle infestazioni da pulci e zecche.</span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;text-align:left"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal">Fipralone Duo Spot On agisce sterilizzando le pulci adulte, inibendo lo sviluppo di uova e larve nell&rsquo;ambiente dopo l&rsquo;applicazione sull&rsquo;animale e interrompendo cos&igrave; il loro ciclo di vita e prevenendo il loro perpetuarsi nell&rsquo;ambiente.</span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;text-align:left"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal">Questa azione si protrae per 12 settimane dopo ogni singola applicazione.</span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;text-align:left"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal">Come in tutti gli spot-on di Formevet, anche le pipette di Fipralone Duo Spot On sono trasparenti per un miglior controllo dell&rsquo;erogazione e sono dotate di un sistema salva-goccia che permette un&rsquo;accurata ed uniforme stesura sul dorso dell&rsquo;animale riducendo cos&igrave; il rischio di effetti collaterali come arrossamenti o prurito nel punto di applicazione.</span></p><p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;height:10pt;text-align:left"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal"></span></p><p id="h.gjdgxs" style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;line-height:1.0;orphans:2;widows:2;text-align:left"><span style="font-size:11pt;font-weight:700">Formato: </span><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:&quot;Trebuchet MS&quot;;font-style:normal">4 pipette da 2,68 ml</span></p>

<p id="h.gjdgxs" style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;text-align:left;"><span style="color:#000000;font-weight:bold;text-decoration:none;vertical-align:baseline;font-size:14pt;font-family:'Trebuchet MS';font-style:normal;">FRONTLINE TRI ACT SOLUZIONE SPOT- ON PER CANI 5-10 KG </span></p> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;height:10pt;text-align:left;"></p> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;text-align:left;"><span style="color:#000000;font-weight:bold;text-decoration:none;vertical-align:baseline;font-size:11pt;font-family:'Trebuchet MS';font-style:normal;">Tutte le caratteristiche di Frontline Tri-Act per cani oltre 5 fino a 10 kg:</span></p> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;height:10pt;text-align:left;"></p> <ul class="lst-kix_list_1-0 start" style="padding:0;margin:0;"> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Prodotto farmaceutico</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Specie di destinazione: cane</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Pipetta con 1 ml di soluzione per cani di taglia piccola da 5 a 10 kg di peso corporeo per il trattamento e la prevenzione di infestazioni da pulci e/o zecche ove sia necessaria l'attività repellente (anti-feeding) nei confronti di flebotomi, mosche cavalline e/o zanzare.</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Per il trattamento e la prevenzione delle infestazioni da pulci Ctenocephalides felis e la prevenzione delle infestazioni da pulci Ctenocephalides canis. Il prodotto elimina le pulci C. felis presenti sull'animale entro 24 ore. Un trattamento previene successive infestazioni da pulci per 4 settimane. </span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Il prodotto può essere usato come parte di un trattamento strategico per la dermatite allergica da pulce ove sia stata precedentemente diagnosticata da un veterinario.</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Il prodotto ha un'efficacia repellente nei confronti delle zecche (Dermacentor reticulatus) da 7 giorni e fino a 4 settimane dal trattamento. Tuttavia, singole zecche possono attaccarsi al cane e staccarsi nelle prime 24 ore dall’infestazione. </span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Il prodotto ha una efficacia acaricida immediata nei confronti di Rhipicephalus sanguineus e Ixodes ricinus, ma è possibile che non vengano eliminate tutte le zecche entro 48 ore dal trattamento se queste sono già presenti al momento dell’applicazione del prodotto. Il prodotto possiede una efficacia acaricida nei confronti delle zecche (Ixodes ricinus, Dermacentor reticulatus, Rhipicephalus sanguineus) persistente per 4 settimane.</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Il prodotto possiede una efficacia repellente (anti-feeding) per 3 settimane nei confronti dei flebotomi (Phlebotomus perniciosus) e per 4 settimane nei confronti delle zanzare (Culex pipiens). Il prodotto ha una efficacia insetticida persistente per 3 settimane nei confronti dei flebotomi (Phlebotomus perniciosus). Il prodotto repelle ed elimina le mosche cavalline (Stomoxys calcitrans) per cinque settimane.</span></li> </ul> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;height:10pt;text-align:left;"></p> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;text-align:left;"><span style="color:#000000;font-weight:bold;text-decoration:none;vertical-align:baseline;font-size:11pt;font-family:'Trebuchet MS';font-style:normal;">Ulteriori indicazioni:</span></p> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;height:10pt;text-align:left;"></p> <ul class="lst-kix_list_3-0 start" style="padding:0;margin:0;"> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Il fipronil è un insetticida e acaricida appartenenete alla famiglia dei fenilpirazoli; elimina le pulci entro 24 ore, le zecche e i pidocchi entro 48 ore dall'esposizione.</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">La permetrina appartiene alla classe dei piretroidi di tipo I, che sono acaricidi e insetticidi dotati di attività repellente. </span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">La permetrina presente nel prodotto fornische attività repellente nei confronti di flebotomi (&lt;80% per 4 setimane), zanzare e zecche.</span></li> </ul> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;height:10pt;text-align:left;"></p> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;text-align:left;"><span style="color:#000000;font-weight:bold;text-decoration:none;vertical-align:baseline;font-size:11pt;font-family:'Trebuchet MS';font-style:normal;">Controindicazioni:</span></p> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;height:10pt;text-align:left;"></p> <ul class="lst-kix_list_5-0 start" style="padding:0;margin:0;"> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Non usare in animali malati o convalescenti o in caso di ipersensibilità nota ai principi attivi o ad uno degli eccipienti.</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Non usare nei gatti o nei conigli, poiché potrebbero verificarsi reazioni avverse potenzialmente mortali.</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Reazioni avverse:</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Tra le molto rare reazioni avverse, dopo l'impiego sono state riscontrate reazioni cutanee transitorie al sito di applicazione (decolorazione della cute, alopecia locale, prurito, arrossamento) e prurito generalizzato o alopecia. Dopo l’uso si sono osservate anche salivazione eccessiva, disturbi neurologici reversibili (aumentata sensibilità agli stimoli, iperattività, tremore muscolare, depressione, altri disturbi nervosi) o vomito.</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Se il cane dovesse leccare il sito di applicazione si possono osservare ipersalivazione transitoria ed emesi. </span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Se dovessero manifestarsi reazioni avverse gravi o altre reazioni non menzionate in questo foglietto illustrativo, si prega di informarne il medico veterinario. </span></li> </ul> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;height:10pt;text-align:left;"></p> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;text-align:left;"><span style="font-weight:bold;font-style:italic;">Composizione (una pipetta da 1 ml contiene):</span><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;"> 67,6 mg fipronil, 504,8 mg permetrina. Eccipiente: 1,125 mg Butilidrossitoluene (E321).</span></p>

<p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;text-align:left;"><span style="color:#000000;font-weight:bold;text-decoration:none;vertical-align:baseline;font-size:14pt;font-family:'Trebuchet MS';font-style:normal;">FRONTLINE TRI ACT SOLUZIONE SPOT ON PER CANI 2- 5 KG </span></p> <p id="h.gjdgxs" style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;height:10pt;text-align:left;"></p> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;text-align:left;"><span style="color:#000000;font-weight:bold;text-decoration:none;vertical-align:baseline;font-size:11pt;font-family:'Trebuchet MS';font-style:normal;">Tutte le caratteristiche di Frontline Tri-Act per cani oltre 2 fino a 5 kg:</span></p> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;height:10pt;text-align:left;"></p> <ul class="lst-kix_list_1-0 start" style="padding:0;margin:0;"> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Prodotto farmaceutico</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Specie di destinazione: cane</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Pipetta con 0,5 ml di soluzione per cani di taglia piccola da 2 a 5 kg di peso corporeo per il trattamento e la prevenzione di infestazioni da pulci e/o zecche ove sia necessaria l'attività repellente (anti-feeding) nei confronti di flebotomi, mosche cavalline e/o zanzare.</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Per il trattamento e la prevenzione delle infestazioni da pulci Ctenocephalides felis e la prevenzione delle infestazioni da pulci Ctenocephalides canis. Il prodotto elimina le pulci C. felis presenti sull'animale entro 24 ore. Un trattamento previene successive infestazioni da pulci per 4 settimane. </span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Il prodotto può essere usato come parte di un trattamento strategico per la dermatite allergica da pulce ove sia stata precedentemente diagnosticata da un veterinario.</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Il prodotto ha un'efficacia repellente nei confronti delle zecche (Dermacentor reticulatus) da 7 giorni e fino a 4 settimane dal trattamento. Tuttavia, singole zecche possono attaccarsi al cane e staccarsi nelle prime 24 ore dall’infestazione.</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Il prodotto ha una efficacia acaricida immediata nei confronti di Rhipicephalus sanguineus e Ixodes ricinus, ma è possibile che non vengano eliminate tutte le zecche entro 48 ore dal trattamento se queste sono già presenti al momento dell’applicazione del prodotto. </span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Il prodotto possiede una efficacia acaricida nei confronti delle zecche (Ixodes ricinus, Dermacentor reticulatus, Rhipicephalus sanguineus) persistente per 4 settimane.</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Il prodotto possiede una efficacia repellente (anti-feeding) per 3 settimane nei confronti di flebotomi (Phlebotomus perniciosus) e per 4 settimane nei confronti delle zanzare (Culex pipiens), e ha una efficacia insetticida persistente per 3 settimane nei confronti dei flebotomi (Phlebotomus perniciosus). Repelle ed elimina le mosche cavalline (Stomoxys calcitrans) per cinque settimane.</span></li> </ul> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;height:10pt;text-align:left;"></p> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;text-align:left;"><span style="color:#000000;font-weight:bold;text-decoration:none;vertical-align:baseline;font-size:11pt;font-family:'Trebuchet MS';font-style:normal;">Ulteriori indicazioni:</span></p> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;height:10pt;text-align:left;"></p> <ul class="lst-kix_list_4-1 start" style="padding:0;margin:0;"> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 72pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Il fipronil è un insetticida e acaricida appartenenete alla famiglia dei fenilpirazoli; elimina le pulci entro 24 ore, le zecche e i pidocchi entro 48 ore dall'esposizione.</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 72pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">La permetrina appartiene alla classe dei piretroidi di tipo I, che sono acaricidi e insetticidi dotati di attività repellente. La permetrina presente nel prodotto fornische attività repellente nei confronti di flebotomi (&lt;80% per 4 setimane), zanzare e zecche.</span></li> </ul> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;height:10pt;text-align:left;"></p> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;text-align:left;"><span style="color:#000000;font-weight:bold;text-decoration:none;vertical-align:baseline;font-size:11pt;font-family:'Trebuchet MS';font-style:normal;">Controindicazioni:</span></p> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;height:10pt;text-align:left;"></p> <ul class="lst-kix_list_5-0 start" style="padding:0;margin:0;"> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Non usare in animali malati o convalescenti o in caso di ipersensibilità nota ai principi attivi o ad uno degli eccipienti.</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Non usare nei gatti o nei conigli, poiché potrebbero verificarsi reazioni avverse potenzialmente mortali.</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Reazioni avverse:</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Tra le molto rare reazioni avverse, dopo l'impiego sono state riscontrate reazioni cutanee transitorie al sito di applicazione (decolorazione della cute, alopecia locale, prurito, arrossamento) e prurito generalizzato o alopecia. Dopo l’uso si sono osservate anche salivazione eccessiva, disturbi neurologici reversibili (aumentata sensibilità agli stimoli, iperattività, tremore muscolare, depressione, altri disturbi nervosi) o vomito.</span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Se il cane dovesse leccare il sito di applicazione si possono osservare ipersalivazione transitoria ed emesi. </span></li> <li style="padding:0;color:#000000;font-size:10pt;line-height:1;font-family:'Trebuchet MS';text-align:left;margin:0 0 0 36pt;"><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;">Se dovessero manifestarsi reazioni avverse gravi o altre reazioni non menzionate in questo foglietto illustrativo, si prega di informarne il medico veterinario. </span></li> </ul> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;height:10pt;text-align:left;"></p> <p style="padding:0;margin:0;color:#000000;font-size:10pt;font-family:'Trebuchet MS';line-height:1;text-align:left;"><span style="font-weight:bold;font-style:italic;">Composizione (una pipetta da 0,5 ml contiene):</span><span style="color:#000000;font-weight:400;text-decoration:none;vertical-align:baseline;font-size:10pt;font-family:'Trebuchet MS';font-style:normal;"> 33,8 mg fipronil, 252,4 mg permetrina. Eccipiente: 0,563 mg Butilidrossitoluene (E321).</span></p>